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Steroid receptors are classic members of the nuclear receptor superfamily that are among the most important drug targets (details). (Dahlman-Wright et al., Pharmacological reviews, 58: 773-781, 2006; Lu et al., Pharmacological reviews, 58:782-797, 2006). AB Vector provides recombinant baculoviruses encoding all major steroid receptor's ligand binding domains (LBDs) in fusion with a GST tag (GST-LBD fusions) under control of strong polyhedrin promoter. We also provide a recombinant baculovirus stock expressing a full-length glucocorticoid receptor. Please inquire about availability of purified steroid receptors at info@abvector.com. Please contact us at info@abvector.com if you are an expert in steroid receptor ligand-binding studies and would like to collaborate on characterization of steroid receptors produced in our FoldHelper™-905c 5-chaperone system as compared to proteins produced in conventional protein expression systems which do not provide extra amounts of Hsp90 and other molecular chaperones. |
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| If you have not worked with recombinant baculoviruses, you can get a quick update at MATERIALS AND METHODS. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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